{"id":16589,"date":"2026-06-19T17:00:00","date_gmt":"2026-06-19T14:00:00","guid":{"rendered":"https:\/\/handoli.com\/index.php\/2026\/06\/19\/this-is-your-brain-on-hormones\/"},"modified":"2026-06-19T17:00:00","modified_gmt":"2026-06-19T14:00:00","slug":"this-is-your-brain-on-hormones","status":"publish","type":"post","link":"https:\/\/handoli.com\/index.php\/2026\/06\/19\/this-is-your-brain-on-hormones\/","title":{"rendered":"This is Your Brain on Hormones"},"content":{"rendered":"<p>After reading something that said her menstrual cycle changes her brain each month, Senior Correspondent Molly Webster goes on a reporting mission to see if that\u2019s true, and, if so, how.<\/p>\n<p>This journey into sex hormones and the brain involves females <i>and <\/i>males, and exacting self-experimentation. It gets into PTSD, and ends with a new twist on self-care (hint: it\u2019s biological). And, it starts to reveal a sneaky truth: that <i>each one of us<\/i> is at the mercy of a crashing sea of chemicals inside of us \u2013 those things we call hormones.<\/p>\n<p><i>Special thanks to Emily Jacobs, <\/i><a href=\"https:\/\/www.pennlinc.io\/team\/laura-pritschet\" rel=\"noopener noreferrer\"><i>Laura Pritschet<\/i><\/a><i>, Pavel Shapturenka, and Dr. Catherine Woolley.<\/i><\/p>\n<p><strong>EPISODE CREDITS:<\/strong><br \/>\n Hosted by &#8211; Molly Webster<br \/>\n Reported by &#8211; Molly Webster<br \/>\n Produced by &#8211; Mona Madgavkar<br \/>\n with help from &#8211; Molly Webster<br \/>\n Fact-checking by &#8211; Diane A. Kelly<\/p>\n<p><strong>EPISODE CITATIONS:<\/strong><\/p>\n<p><strong>Articles &#8211;\u00a0<\/strong><br \/>\n **<i>The experiments we feature in this episode are called: 28andMe, 28andOC, and 28andHe, all of which took place at Emily Jacobs lab at the University of California, Santa Barbara.**\u00a0<\/i><\/p>\n<ul>\n<li><a href=\"https:\/\/jacobs.psych.ucsb.edu\/research\/28-and-me\" rel=\"noopener noreferrer\"><i>The 28 Project<\/i><\/a> (https:\/\/zpr.io\/CSx6MnwZjRvp), background from the Jacobs lab<\/li>\n<\/ul>\n<p>For more on how much variability there is between female and male animals, check out this \u201cgroundbreaking\u201d study, referenced by Emily Jacobs in our episode<\/p>\n<ul>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3008499\/\" rel=\"noopener noreferrer\"><i>Sex Bias in Neuroscience and Biomedical Research<\/i><\/a>(<a href=\"https:\/\/zpr.io\/ZRgKZzdNejUA\" rel=\"noopener noreferrer\">https:\/\/zpr.io\/ZRgKZzdNejUA<\/a>),\u00a0 by Beery AK, Zucker I., Neurosci Biobehav Rev. 2011<\/li>\n<\/ul>\n<p>Dr. Catherine Woolley has revolutionized the field of neuroscience and sex hormones, here\u2019s more about her work \u2026<\/p>\n<ul>\n<li><a href=\"https:\/\/www.the-scientist.com\/sex-differences-in-the-brain-get-down-to-the-molecular-level-73768\" rel=\"noopener noreferrer\"><i>Sex Differences in the Brain Get Down to the Molecular Level Sex<\/i><\/a> (<a href=\"https:\/\/zpr.io\/UNCLE9J782N5\" rel=\"noopener noreferrer\">https:\/\/zpr.io\/UNCLE9J782N5<\/a>), by Stephanie DeMarco, PhD, The <a href=\"http:\/\/scientist.com\/\" rel=\"noopener noreferrer\">Scientist.com<\/a><\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/j.1528-1157.1998.tb02601.x\" rel=\"noopener noreferrer\"><i>Hormonal Effects on the Brain<\/i><\/a> (<a href=\"https:\/\/zpr.io\/DvNM9EkXdtGG\" rel=\"noopener noreferrer\">https:\/\/zpr.io\/DvNM9EkXdtGG<\/a>), by Woolley, C.S. and Schwartzkroin, P.A. Epilepsia<\/li>\n<\/ul>\n<p><strong>Data sets &#8211;<\/strong><\/p>\n<ul>\n<li><a href=\"http:\/\/openneuro.org\/datasets\/ds002674\/versions\/1.0.6\" rel=\"noopener noreferrer\"><i>28andMe and 28andOC<\/i><\/a> (<a href=\"https:\/\/zpr.io\/hbXVNTVp2Q7j\" rel=\"noopener noreferrer\">https:\/\/zpr.io\/hbXVNTVp2Q7j<\/a>):<\/li>\n<li><a href=\"https:\/\/openneuro.org\/datasets\/ds005115\/versions\/1.2.0\" rel=\"noopener noreferrer\"><i>28andHe<\/i><\/a> (<a href=\"https:\/\/zpr.io\/sZXhfMbMwKb7\" rel=\"noopener noreferrer\">https:\/\/zpr.io\/sZXhfMbMwKb7<\/a>)<\/li>\n<\/ul>\n<p><strong>Audio &#8211;\u00a0<\/strong><br \/>\n In the episode, we mention Dr. Russ Poldrack and the Midnight Scan Club, as inspo for self-experimentation<\/p>\n<ul>\n<li><a href=\"https:\/\/www.sciencefriday.com\/segments\/the-midnight-scan-club\/\" rel=\"noopener noreferrer\"><i>The Midnight Scan Club<\/i><\/a> (<a href=\"https:\/\/zpr.io\/CLBhNQSxK844\" rel=\"noopener noreferrer\">https:\/\/zpr.io\/CLBhNQSxK844<\/a>), by Science Friday.<br \/>\n  \u00a0<\/li>\n<\/ul>\n<p><i>Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. <\/i><a href=\"https:\/\/radiolab.org\/newsletter\" rel=\"noopener noreferrer\"><i>Sign up<\/i><\/a><i> (https:\/\/radiolab.org\/newsletter)!<\/i><\/p>\n<p><i>Radiolab is supported by listeners like you. Support Radiolab by becoming a member of <\/i><a href=\"http:\/\/members.radiolab.org\/\" rel=\"noopener noreferrer\"><i>The Lab<\/i><\/a><i> (https:\/\/members.radiolab.org\/) today.<\/i><\/p>\n<p><i>Follow our show on <\/i><a href=\"http:\/\/instagram.com\/radiolab\" rel=\"noopener noreferrer\"><i>Instagram<\/i><\/a><i>, <\/i><a href=\"http:\/\/twitter.com\/radiolab\" rel=\"noopener noreferrer\"><i>Twitter<\/i><\/a><i> and <\/i><a href=\"http:\/\/facebook.com\/radiolab\" rel=\"noopener noreferrer\"><i>Facebook<\/i><\/a><i> @radiolab, and share your thoughts with us by emailing <\/i><a href=\"mailto:radiolab@wnyc.org\" rel=\"noopener noreferrer\"><i>radiolab@wnyc.org<\/i><\/a><i>.<\/i><\/p>\n<p><i>Leadership support for Radiolab\u2019s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.<\/i><\/p>\n<p> <\/p>\n<p>Hosted by Simplecast, an AdsWizz company. See <a href=\"https:\/\/pcm.adswizz.com\/\">pcm.adswizz.com<\/a> for information about our collection and use of personal data for advertising.<\/p>","protected":false},"excerpt":{"rendered":"<p>After reading something that said her menstrual cycle changes her brain each month, Senior Correspondent Molly Webster goes on a reporting mission to see if that\u2019s true, and, if so, how. This journey into sex hormones and the brain involves females and males, and exacting self-experimentation. It gets into PTSD, and ends with a new [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":16590,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":[],"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[15],"tags":[],"class_list":["post-16589","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-world"],"_links":{"self":[{"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/posts\/16589","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/comments?post=16589"}],"version-history":[{"count":0,"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/posts\/16589\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/media\/16590"}],"wp:attachment":[{"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/media?parent=16589"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/categories?post=16589"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/handoli.com\/index.php\/wp-json\/wp\/v2\/tags?post=16589"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}